Improved antibody production in Chinese hamster ovary cells by ATF4 overexpression
نویسندگان
چکیده
منابع مشابه
Using transient transfected Chinese hamster ovary (CHO) cells by pET28a-LIC-NTF4 in gene therapy
Introduction: Neurotrophins, as a family of proteins, are responsible for induction of the survival, development, and function of neurons. Also, neurotropic factors are growth factors like Neurotrophins that help neurons survive. Moreover, Neurotrophins differentiate between progenitor cells so that neurons are formed. Despite the fact that the majority of mammalian brain neurons are produced p...
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The nucleus of a mammalian cell undergoes profound reorganization when the cell enters mitosis and a number of proteins involved at various levels of the cell cycle have been characterized. The presence of mitotic-specific proteins has been reported and their roles are important in understanding the mechanics of cell division. The ability of antibodies to recognize mitotic protein antigens and ...
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Introduction The endoplasmic reticulum (ER) is the major organelle of synthesis of protein and forms a membranous network throughout the cell. According to Shimizu and Hendershot [1], about one third of the total proteins produced are synthesized in the ER. The ER lumen possesses a unique environment for high quality control for protein folding and assembly. It contains high concentrations of m...
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ژورنال
عنوان ژورنال: Cytotechnology
سال: 2013
ISSN: 0920-9069,1573-0778
DOI: 10.1007/s10616-013-9631-x